7 Yet whatever gains I had, these I have come to regard as loss because of Christ. 8 More than that, I regard everything as loss because of the surpassing value of knowing Christ Jesus my Lord. For his sake I have suffered the loss of all things, and I regard them as rubbish, in order that I may gain Christ 9 and be found in him, not having a righteousness of my own that comes from the law, but one that comes through faith in Christ, the righteousness from God based on faith. 10 I want to know Christ and the power of his resurrection and the sharing of his sufferings by becoming like him in his death, 11 if somehow I may attain the resurrection from the dead. 12 Not that I have already obtained this or have already reached the goal; but I press on to make it my own, because Christ Jesus has made me his own. 13 Beloved, I do not consider that I have made it my own; but this one thing I do: forgetting what lies behind and straining forward to what lies ahead, 14 I press on toward the goal for the prize of the heavenly call of God in Christ Jesus.
15 Let those of us then who are mature be of the same mind; and if you think differently about anything, this too God will reveal to you. 16 Only let us hold fast to what we have attained.

“I regard everything as loss” – Not that everything must be gone (though for Paul, all had been stripped away). Our attitude toward things in our lives is as though they were not. Cling to nothing but Christ. Depend on nothing but God. Rely on nothing but the power of the Holy Spirit that is yours by grace through faith.
My prayer lately has been, “Lord Jesus Christ, Son of God, Savior, let me be with you in the center of the Father’s will.” Every thought, action, attitude, desire, is brought into submission to the Father’s will. This is the intent beneath the phrase in The Lord’s Prayer, “Your kingdom come, Your will be done, on earth as it is in heaven.”
And I press on. When discouragement rises, I press on. When resistance presses, I press on. When conflict stirrs, I press on. I do not press on, necessarily, toward a particular solution. It would be a misreading of the text to think that we ought never to reconsider a particular course of action when faced with resistance. I think rather that we press on toward the goal, which may mean finding another route to get there. But, either way, we do not loose focus on our purpose, why we are here, and who we have been called to serve.